Management of Non-Union With Pulsed, Low-Intensity Ultrasound Therapy - International Results
Abstract: In prospective, randomized, double-blind, placebo-controlled, multi-center clinical studies, pulsed, lowintensity ultrasound has been proven to be effective in decreasing the time to heal in both fresh diaphyseal (tibia) and metaphyseal (distal radius) fractures. It also decreases the likelihood of a delayed union (>150 days to heal) in tibia fractures and loss of reduction in distal radius fractures. World-wide clinical studies, using pulsed, low-intensity ultrasound for treatment of non-union in a self-paired control study design, have demonstrated a heal rate of 88% with an average treatment time of 4.5 months in non-unions and an average fracture age of 23 months. The therapy is safe and non-invasive, and is used by the patient at home for a 20-minute treatment session per day. Authors: Victor H. Frankel, M.D., Ph.D., K.N.O., Kosaku Mizuno, M.D., Ph.D. |
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